Inflammatory Responses of Bovine Polymorphonuclear Neutrophils Induced by Staphylococcal Enterotoxin C via Stimulation of Mononuclear Cells

Stimulation of Mononuclear Cells Staphylococcal Enterotoxin C via by Polymorphonuclear Neutrophils Induced Inflammatory Responses of Bovine

Inflammatory responses of bovine polymorphonuclear neutrophils induced by staphylococcal enterotoxin C via stimulation of mononuclear cells.

To elucidate the pathological roles of staphylococcal enterotoxin C (SEC) in bovine staphylococcal mastitis, a histopathological analysis of SEC-inoculated mammary glands was performed. SEC-inoculated mammary glands exhibited interstitial inflammation, and the leukocytes that migrated into the gland were predominantly polymorphonuclear neutrophils (PMN). In the gland cistern tissues dissected f...

Activation of bovine lymphocyte subpopulations by staphylococcal enterotoxin C.

Staphylococcus aureus is a major mastitis-causing pathogen in cattle. The chronic nature of bovine staphylococcal mastitis suggests that some products or components of S. aureus may interfere with the development of protective immunity. One class of molecules that could be involved are superantigens (SAgs). Although a significant number of mastitis isolates produce SAgs, the effect of these mol...

Staphylococcal Enterotoxin H Induced Apoptosis of Bovine Mammary Epithelial Cells in Vitro

Staphylococcal enterotoxins (SEs) are powerful superantigenic toxins produced by Staphylococcus aureus (S. aureus). They can cause food poisoning and toxic shock. However, their impact on bovine mammary epithelial cells (bMECs) is still unknown. In this study, the distribution of SE genes was evaluated in 116 S. aureus isolates from bovine mastitis, and the most prevalent genes were seh (36.2%)...

Activation of dendritic cells by polymorphonuclear neutrophils.

The obsolete view describing neutrophils as innate immune cells that respond rapidly to microbial invasion and then rapidly die by apoptosis is now challenged by several data. In both human and mice, there are now evidences that neutrophils play a role in dendritic cell activation, a critical step for the outcome of the specific T cell response.